abstract：:Previous studies using various excitatory amino acid antagonists have shown that synaptic transmission between the auditory nerve and the cochlear nucleus of chickens (nuc. magnocellularis; NM) is mediated by non-N-methyl-D-aspartate (non-NMDA) receptors. In the present study we have attempted to define the subclass o...

journal_title：Neuroscience letters

authors： Nemeth EF,Jackson H,Parks TN

更新日期：1985-09-06 00:00:00

abstract：:Motor nerve supplies to 15 poles of rat lumbrical spindle were reconstructed from serial, 1-micron transverse sections of muscle embedded in resin. Neural and muscular elements associated with the modulation of static sensitivity of afferents were deficient in these spindles relative to cat tenuissimus and rat soleus ...

journal_title：Neuroscience letters

authors： Walro JM,Kucera J

更新日期：1985-09-06 00:00:00

abstract：:A comparative study was made of the enzyme choline acetyltransferase (ChAT) from normal and Alzheimer (senile dementia of the Alzheimer type) brain. The number of molecular weight and charge forms of the enzyme were determined in the caudate region of both brains. Efficient purification of active ChAT was achieved usi...

journal_title：Neuroscience letters

authors： Bruce G

更新日期：1985-08-30 00:00:00

abstract：:Mice were treated with N-2-chloroethyl-N-ethyl-2-bromobenzylamine hydrochloride (DSP4), which causes severe noradrenaline (NA) depletions in brain regions and the spinal cord, or vehicle i.p. They were tested 14 days later for antinociception induced by intrathecal injections of different doses of NA. A potentiation o...

journal_title：Neuroscience letters

authors： Post C,Arweström E,Minor BG,Wikberg JE,Jonsson G,Archer T

更新日期：1985-08-16 00:00:00

abstract：:A new modification of the nicotinamide adenine dinucleotide phosphate (NADPH)-diaphorase reaction was used to study the distribution of a specific subset of neurons in rat striatum. These neurons are known to also contain somatostatin-like immunoreactivity (SLI). We have previously found a heterogeneous distribution o...

journal_title：Neuroscience letters

authors： Kowall NW,Beal MF,Ferrante RJ,Martin JB

更新日期：1985-08-16 00:00:00

abstract：:We examined the caudate spindle in control and pargyline-pretreated rats following bilateral application of 3 doses (15, 50 and 150 micrograms/site) of dopamine (DA) into the caudate nucleus. The highest dose of DA (150 micrograms) suppressed the spindle, whereas lower doses (15, 50 micrograms) enhanced the spindle in...

journal_title：Neuroscience letters

authors： Okuyama S,Hashimoto S,Aihara H

更新日期：1985-08-16 00:00:00

abstract：:We examined the distribution of ferric ion-ferrocyanide stain (a marker for excitable regions of myelinated fibers) in the lead-induced demyelinating neuropathy of the rat. By electron microscopy, we found that paranodal degeneration resulted in spreading of the reaction product from nodal to internodal axolemma. Duri...

journal_title：Neuroscience letters

authors： Coria F,Silos I,Fernandez R,Monton F,Lafarga M

更新日期：1985-08-05 00:00:00

abstract：:Kainic acid (KA) has been largely used as a neurotoxin, and its axon-sparing effect being repeatedly emphasized, on the basis of anatomical and biochemical data. The present study examines this 'axon-sparing' effect from an electrophysiological point of view and demonstrates that lemniscal fibers retain the capacity t...

journal_title：Neuroscience letters

authors： Peschanski M,Briand A,Poingt JP,Guilbaud G

更新日期：1985-08-05 00:00:00

abstract：:By the use of light microscopic immunohistochemistry it was shown that a significant population of small primary sensory afferents of guinea pig contains immunoreactivities to antisera directed against prodynorphin-opioid peptides, whereas immunoreactivities to antisera directed against opioid peptides exclusively con...

journal_title：Neuroscience letters

authors： Weihe E,Hartschuh W,Weber E

更新日期：1985-08-05 00:00:00

abstract：:Previous studies using 2-deoxyglucose (2-DG) autoradiography have demonstrated that the suprachiasmatic nucleus (SCN) of the hypothalamus, a putative neural circadian pacemaker, displays circadian rhythmicity in its metabolic activity. In the present study, we show that distinct circadian variations in 2-DG uptake occ...

journal_title：Neuroscience letters

authors： Rosenwasser AM,Trubowitsch G,Adler NT

更新日期：1985-07-31 00:00:00

abstract：:Afferent fibers ending in nerve-end neuromas generate spontaneous impulse discharge which has been implicated as a cause of paraesthesias and pain following peripheral nerve injury in man. We now show in rats that the anticonvulsant drug phenytoin (PT), applied systemically or topically onto desheathed neuromas, suppr...

journal_title：Neuroscience letters

authors： Yaari Y,Devor M

更新日期：1985-07-04 00:00:00

abstract：:Sympathoexcitatory neurons in the C1 adrenergic area of the rostral ventrolateral medulla (RVL) are tonically inhibited by gamma-aminobutyric acid (GABA). To identify the source of this GABAergic input, the distribution of neurons containing glutamate decarboxylase (GAD) was determined immunocytochemically in rats tre...

journal_title：Neuroscience letters

authors： Meeley MP,Ruggiero DA,Ishitsuka T,Reis DJ

更新日期：1985-07-04 00:00:00

abstract：:Pargyline, an inhibitor of monoamine oxidase (MAO), prevented 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced inhibition of dihydroxyphenylalanine (DOPA) production by tyrosine hydroxylase (TH) system in rat striatal tissue slices. The result suggests that the metabolism of MPTP in rat striatal tissue slic...

journal_title：Neuroscience letters

authors： Hirata Y,Nagatsu T

更新日期：1985-06-24 00:00:00

abstract：:The survival of identified retinal ganglion cells (RGGs) in vitro increased when they were plated over subcultured monolayers of astrocytes. Immunofluorescence labelling of these monolayers showed that over 85% of the cells were glial fibrillary acidic protein (GFAP) positive and consisted of large, flat immature astr...

journal_title：Neuroscience letters

authors： McCaffery CA,Raju TR,Bennett MR

更新日期：1985-06-24 00:00:00

abstract：:The present study was undertaken to investigate whether benzodiazepine receptors are involved in either the anticonvulsant activity of phenytoin against supramaximal seizures or maximal threshold seizures induced by electroshock or the neurotoxicity of phenytoin. Ro 15-1788, a benzodiazepine receptor antagonist, rever...

journal_title：Neuroscience letters

authors： Chweh AY,Swinyard EA,Wolf HH

更新日期：1985-06-24 00:00:00

abstract：:6-day-old mice pups were injected with D-amino acids (D-phenyl-alanine + D-leucine), and their ultrasonic distress vocalizations were measured. D-Amino acids, which exert opioid-like effects, reduce the number of ultrasonic calls without affecting the activity of the pups. This effect is reversed by naloxone, an opioi...

journal_title：Neuroscience letters

authors： Albonetti ME,D'Udine B,Oliverio A

更新日期：1985-06-24 00:00:00

abstract：:The pattern and distribution of the cortical projections from intermediate parts of the cholinergic basal magnocellular nucleus were studied by anterogradely transported Phaseolus vulgaris-leucoagglutinin. This immunocytochemical tracing technique reveals the detailed morphology and distribution of efferents from this...

journal_title：Neuroscience letters

authors： Luiten PG,Spencer DG Jr,Traber J,Gaykema RP

更新日期：1985-06-12 00:00:00

abstract：:The effect of methionine-enkephalin (Met-Enk) on responses of rat brain neostriatum neurones to microiontophoretic application of glutamate was studied in experiments with extracellular recording of spike activity. Met-Enk administered by microiontophoresis was shown to depress the glutamate-induced responses. In para...

journal_title：Neuroscience letters

authors： Kuznetsov VI,Godukhin OV

更新日期：1985-06-12 00:00:00

abstract：:In a light microscopic study the ferric ion-ferrocyanide staining of the squid giant axon was investigated. In other neurons this stain is known to indicate excitable membranes with high sodium channel density, such as the node of Ranvier or the initial segment. In the squid the stain reacted in small patches of the a...

journal_title：Neuroscience letters

authors： Greeff NG,Akert K,Sandri C

更新日期：1985-06-12 00:00:00

abstract：:The action of some cholinergic drugs has been studied on the field potentials evoked by orthodromic stimulation of the lateral olfactory tract (LOT) in guinea-pig olfactory cortex slices maintained in vitro. A reversible depression of the electrically evoked surface-negative field potential (N-wave) was seen following...

journal_title：Neuroscience letters

authors： Williams SH,Constanti A,Brown DA

更新日期：1985-05-23 00:00:00

abstract：:Silver staining (Bodian procedure) in the nucleus of the sublenticular substantia innominata (SI), also referred to as the nucleus basalis of Meynert, was evaluated in autopsy material from patients with Alzheimer's disease or senile dementia of the Alzheimer type (age at death: mean 69 years, range 63 to 81 years; ti...

journal_title：Neuroscience letters

authors： Jacobs RW,Farivar N,Butcher LL

更新日期：1985-05-23 00:00:00

abstract：:N-Methyl-D-aspartate (NMDA), quisqualate, kainate and potassium increased, in a dose-dependent manner, the efflux of radioactivity from rat cerebral cortex minislices preincubated with [3H]choline. Ketamine (1-5 microM) and magnesium (0.1-1 mM) reduced only the release evoked by NMDA. The non-parallel shift of the NMD...

journal_title：Neuroscience letters

authors： Lodge D,Johnston GA

更新日期：1985-05-23 00:00:00

abstract：:The light microscopic localization of gamma-aminobutyric acidB (GABAB) receptors in the rat brain has been accomplished using in vitro autoradiography with [3H]baclofen as a ligand. Initial biochemical studies indicated this compound specifically bound to slide-mounted tissue sections with high affinity in a saturable...

journal_title：Neuroscience letters

authors： Gehlert DR,Yamamura HI,Wamsley JK

更新日期：1985-05-14 00:00:00

abstract：:In urethane-anesthetized rats, injections of 50 pmol of arginine-vasopressin (AVP) or thyrotropin-releasing hormone (TRH) into a lateral cerebral ventricle (i.c.v.) elicit short-latency increases in blood pressure. i.c.v. injection of 50 pmol of the AVP antagonist, d(CH2)5Tyr(Me)AVP, but not of the vehicle (artificial...

journal_title：Neuroscience letters

authors： Pittman QJ,Franklin LG

更新日期：1985-05-14 00:00:00

abstract：:Microelectrode recordings from the somata of rat dorsal root ganglion (DRG) cells were used to correlate their electrophysiological characteristics with sensitivity to locally applied capsaicin. Of the 80 cells tested, 17 responded to capsaicin by a rapid depolarization. These cells had low axonal conduction velocitie...

journal_title：Neuroscience letters

authors： Heyman I,Rang HP

更新日期：1985-05-01 00:00:00

abstract：:The ultrastructure of astrocytic foot processes at the glia limitans in rat optic nerve was studied by freeze-fracture. Two classes of astrocytic end-foot processes were observed. Most astrocytic foot processes in this region show a high density of orthogonal arrays of P-face particles (assemblies) that are randomly o...

journal_title：Neuroscience letters

authors： Black JA,Waxman SG

更新日期：1985-04-19 00:00:00

abstract：:Both substance P (SP)- and epinephrine-containing neurons in the rostral ventrolateral medulla have been thought to play a role in regulating vasomotor tone. The combination of retrograde transport of a fluorescent dye (Fast Blue) and immunofluorescent staining for SP- and phenylethanolamine-N-methyltransferase (PNMT)...

journal_title：Neuroscience letters

authors： Lorenz RG,Saper CB,Wong DL,Ciaranello RD,Loewy AD

更新日期：1985-04-19 00:00:00

abstract：:Retrograde axonal transport and fluorescent retrograde labelling of neurons were investigated in a crustacean motor system. A fluorescent tracer (Granular blue) was injected into an antennal muscle of rock lobster in order to identify the motor neurons innervating it. After an appropriate post-injection survival time,...

journal_title：Neuroscience letters

authors： Rossi-Durand C,Sorensen KE

更新日期：1985-04-09 00:00:00

abstract：:Injections of a wheat germ agglutinin-horseradish peroxidase conjugate were placed in representative areas of the cerebellar cortex of adult tree shrews. Retrogradely labeled cells were found in the medial terminal nucleus (MTN) of the accessory optic system (AOS) when ventral portions of the uvula were involved in th...

journal_title：Neuroscience letters

authors： Haines DE,Sowa TE

更新日期：1985-04-09 00:00:00

abstract：:Cultures were produced from retinas taken from human foetuses. Specific cells in culture have the capacity to take up exogenous serotonin, which was then visualized by immunofluorescence using an antisera to serotonin. The known serotonergic uptake blocker, chlorimipramine, inhibited the uptake of the amine while benz...

journal_title：Neuroscience letters

authors： Osborne NN,Beaton DW

更新日期：1985-04-09 00:00:00

abstract：:Rabbit retinal Müller cells were isolated by means of papaine and mechanical dissociation. These cells were shown to have a well preserved morphology and to preserve viability for many hours. Intense wheat germ agglutinin binding occurs on the photoreceptor side of Müller cells, especially in the microvillous region. ...

journal_title：Neuroscience letters

authors： Reichenbach A,Dettmer D,Brückner G,Neumann M,Birkenmeyer G

更新日期：1985-03-22 00:00:00

abstract：:The number of granule cell dendritic spines per micrometer of dendritic length in the dorsal and ventral leaves of the dentate gyrus was quantified using light microscopic-Golgi preparations of normal adult rats. Spines were counted in terms of 3 categories of spine form for the 3 afferent termination zones of the mol...

journal_title：Neuroscience letters

authors： Desmond NL,Levy WB

更新日期：1985-03-15 00:00:00

abstract：:This paper describes in detail the acetylcholinesterase (AChE) staining characteristics of the normal human amygdaloid complex using fixed post-mortem brain tissue. It was shown that the differential AChE staining of the amygdala could be used to accurately delineate amygdaloid subdivisions macroscopically. Using the ...

journal_title：Neuroscience letters

authors： Svendsen CN,Bird ED

更新日期：1985-03-15 00:00:00

abstract：:After short periods of intense sympathetic activation, the action of the vagus nerve on heart rate is inhibited for periods of many minutes to several hours. This effect is not abolished by effective blockade of alpha- or beta-adrenoceptors and is not duplicated by administration of noradrenaline or isoprenaline. A si...

journal_title：Neuroscience letters

authors： Potter EK

更新日期：1985-03-15 00:00:00

abstract：:Ablation of the frog's nucleus isthmi results in a visual scotoma contralateral to the lesion. Within the scotoma, animals do not respond to visually presented prey or threats. The locus of visual loss is related to the area of isthmal tissue ablated. With complete unilateral ablation, a frog displays no visually elic...

journal_title：Neuroscience letters

authors： Caine HS,Gruberg ER

更新日期：1985-03-15 00:00:00

abstract：:In an attempt to elucidate the possible mechanisms involved in the development of the thermoregulatory disturbances induced by systemic capsaicin treatment, the effects of 5-HT injected into the preoptic region or into the cisterna magna on the body temperature and on tail skin vasodilation were studied in control and...

journal_title：Neuroscience letters

authors： Hajós M,Obál F Jr,Jancsó G,Obál F

更新日期：1985-02-28 00:00:00

abstract：:Using immunohistochemical techniques, we demonstrate aspartate aminotransferase (AAT)-like immunoreactivity in cone pedicles and ganglion cells of the cat retina. An identical pattern was seen when we stained for cytochrome oxidase activity, a marker for neurons which have a high metabolic activity. Tetrodotoxin selec...

journal_title：Neuroscience letters

authors： Bolz J,Thier P,Brecha N

更新日期：1985-02-04 00:00:00

abstract：:Neurons in the ipsilateral anteropolar division of the zona incerta were retrogradely labeled following injections of horseradish peroxidase in the main olfactory bulb. In addition, labeled cell bodies were found in the dorsal hypothalamus. Fewer and less densely labeled neuron cell bodies were seen in the contralater...

journal_title：Neuroscience letters

authors： Uemura-Sumi M,Osterstock J,Millhouse OE

更新日期：1985-02-04 00:00:00

abstract：:The distribution of L-3,4-dihydroxy-[3H]phenylalanine (L-[3H]DOPA) was examined in rats following i.v. injection, to ascertain the possible usefulness of using this ligand to image dopaminergic systems using positron emission tomography. It was found that L-DOPA and its metabolites were preferentially localized in the...

journal_title：Neuroscience letters

authors： Liskowsky DR,Potter LT

更新日期：1985-01-21 00:00:00

abstract：:Doxorubicin, a fluorescent retrograde neurotoxin, killed neurons in the ventral tegmentum and thalamus that were afferent to the injection site in the caudate-putamen. The neurotoxic effects in the ventral tegmentum and thalamus were prevented by a large coronal knife cut caudal to the injection site in the striatum, ...

journal_title：Neuroscience letters

authors： van der Kooy D,Zito KA,Roberts DC

更新日期：1985-01-21 00:00:00